学会発表presentation

SMCラボラトリーズは、製薬企業や研究機関のご要望に沿った試験をデザインするコンサルティング型の
CROとして世界的に⾼い評価をいただいています。
特にMASH/NASHの研究分野では、当社独⾃のSTAM™マウスを提供しており、
STAM™マウスを用いた研究成果は雑誌や学会などで多く公表されております。

Presentations

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No.55

2017

First EASL NAFLD Summit 2017,

“Dual CCR2/5 antagonist decreases hepatic inflammation in acute liver injury and NASH metabolic animal models” Pfizer Inc.

No.54

2017

First EASL NAFLD Summit 2017,

“AXA1125, a novel defined amino acid composition (DAAC), improves NAFLD activity score (NAS) and reduces fibrosis in two rodent models of nonalcoholic steathepatitis (NASH)” Axcella Health, Inc.

No.53

2017

AASLD 2017,

“The Anti-Fibrogenic and Liver Protective Effects of Namodenoson (CF102) in a Non-Alcoholic Steatohepatitis Model” Can-Fite BioPharma Ltd.

No.52

2017

AASLD 2017,

“DPP4 Inhibitor Suppressed Progression of NASH-related Hepatocellular Carcinoma with Inhibition of Metabolic Reprograming in p62-Keap 1-Nrf2-pentose Phosphate Pathway in a Mouse Model: A Metabolomic Analysis” Kurume University School of Medicine

No.51

2017

AASLD 2017,

“CB4209 and CB4211 Reduce the NAFLD Activity Score in the STAM™ Model of NASH, Reduce Triglyceride Levels, and Induce Selective Fat Mass Loss in DIO Mice” CohBar, Inc.

No.50

2017

AASLD 2017,

“Combination Treatment of LJN452 and Cenicriviroc Snows Additive Effects in a Diet-Induced NASH Model” Genomics Institute of the Novartis Research Foundation/Allergan plc/Novartis Institutes for BioMedical Research, Inc.

No.49

2017

AASLD 2017,

“Gemcabene Attenuates the NAFLD Activity and Fibrosis Scores, and Downregulates Hepatic Inflammatory Genes in the STAM™ Murine Model of NASH-HCC” Gemphire Therapeutics Inc.

No.48

2017

DDW 2017,

“A HMG-CoA Reductase Inhibitor, Rosuvastatin, as a Potential Preventive Drug for The Development of Hepatocellular Carcinoma Associated With Non-alcoholic Fatty Liver Disease in Mice” Osaka Medical College

No.47

2017

EASL the International Liver CongressTM 2017,

“Anti-fibrotic effect of NV556,a sanglifehrin-based cyclophilin inhibitor,in a preclinical model of non-alcoholic steatohepatitis” Neuro Vive Pharmaceutical AB

No.46

2017

AACR 2017,

“Inhibition of gene expression during non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis is mediated by histone H4 lysine 16 deacetylation” FDA-National Center for Toxicological Research.

No.45

2017

AACR 2017,

“Alterations in the chromatin accessibility in nonalcoholic steatohepatitis-associated hepatocellular carcinoma” FDA-National Center for Toxicological Research

No.44

2017

AACR 2017,

“Role of miRNAome deregulation in the pathogenesis of non-alcoholic steatohepatitis (NASH)-derived hepatocellular carcinoma” FDA-National Center for Toxicological Research

No.43

2017

AASLD 2017,

Emerging Trends Conference: Emerging Trends in Non-Alcoholic Fatty Liver Disease, “The Novel Antidiabetic Candidate MTBL0036 Greatly Diminishes The NAFLD Activity Score in The STAM™ Mouse Model of NASH” Metabolys Inc.

No.42

2017

AASLD 2017,

Emerging Trends Conference: Emerging Trends in Non-Alcoholic Fatty Liver Disease, “DUR-928, An Endogenous Regulatory Molecule, Exhibits Anti-Inflammatory and Antifibrotic Activity in a Mouse Model of NASH” DURECT Corporation