PUBLICATION
SMC Laboratories is highly regarded worldwide as a consulting CRO that designs studies in line with the demands of pharmaceutical companies and research institutions.
In particular, in the NASH-HCC field, SMC is a highly regarded CRO, because of our unique STAM™ mice.
The results achieved with our STAM™ have been introduced in academic publications as well as scientific conferences.
Publications
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No.49
International Journal of Molecular Medicine,
“The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice.” (Int J Mol Med, 44(6):2256-2264, 2019)
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No.48
Science Translational Medicine,
“Targeting diacylglycerol acyltransferase 2 for the treatment of nonalcoholic steatohepatitis” (Sci Transl Med., 11(520), 2019)
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No.47
Cells,
“Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis” (Cells, 8;8(11), 2019)
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No.46
International Journal of Molecular Sciences,
“The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma”(Int. J. Mol. Sci. , 20(20), 5237, 2019)
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No.45
Toxicological Sciences,
“Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.”(Toxicol Sci., 170(2):273-282, 2019)
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No.44
Biochemistry,
“A Panel of Protein Kinase Chemosensors Distinguishes Different Types of Fatty Liver Disease” (Biochemistry, 58(37):3911-3917, 2019)
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No.43
Hepatology Communications,
“Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents“ (Hepatol Commun., 3(8): 1085–1097, 2019)
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No.42
International Journal of Gastroenterology,
"Characterization of EDP-305, a Highly Potent and Selective Farnesoid X Receptor Agonist, for the Treatment of Non-alcoholic Steatohepatitis" (International Journal of Gastroenterology, DOI: 10.11648/j.ijg.20190301.12, 2019)
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No.41
Experimental Animals,
"Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM™ mice" (Exp Anim., DOI: 10.1538/expanim.18-0152, 2019)
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No.40
Frontiers in Genetics,
"Gene Expression and DNA Methylation Alterations During Non-alcoholic Steatohepatitis-Associated Liver Carcinogenesis" (Front Genet., May 29;10:486, 2019)
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No.39
Journal of Cellular and Molecular Medicine,
"The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis" (J Cell Mol Med., 23:1759-1770, 2019)
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No.38
Scientific Reports,
"Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan" (Sci Rep., Mar 8;9(1):4003, 2019)
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